תוכנית מדעית

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2 Scientific Program Day 1 Thursday, April 19, :00-14:00 Reception & Lunch, Professional exhibition 14:00-14:05 Greetings & Opening Remarks 14:05-14:15 ISNH Registry - Annual report Dr. Eliezer Golan 14:15-15:45 Session 1: Hemodialysis. Chairpersons: Dr. Gabi Morduchowicz, Dr. David Tovbin 14:15 Timing of the first cannulation of Arteriovenous Hemodialysis graft had no effect on graft suvival Leonid Feldman, Jabir Mursi, Ilia Beberashvili, Joshua Weissgarten. Nephrology Dept. Assaf Harofeh Medical Center, Zrifin Arie Bass, Igor Rabin. Vascular Surgery Dept. Assaf Harofeh Medical Center, Zrifin 14:30 The role of nutritional scores for serial monitoring of nutritional status in Hemodialysis patients Ilia Beberashvili, Inna Sinuani, Gregory Shapiro, Leonid Feldman, Zhan Averbukh, Joshua Weissgarten. Nephrology Dept. Assaf Harofeh Medical Center, Zrifin Ada Azar, Hadas Kadoshi, Nutrition Dept. Assaf Harofeh Medical Center, Zrifin 14:45 Implementing individual hemodialysis (HD) dialysate Na concentration (DNa) David Tovbin, Ana Basok, Lina Schwarz, Lea Michaelashvilli, Moshe Zlotnik. Nephrology, Soroka University Medical Center, Be'er Sheva Jakob Nowotny. Medical School for International Health in collaboration with Columbila Universety, Be'er Sheva 15:00 Effect of timing Thrombectomy on survival fo Thrombosed Arteriovenous Hemodialysis grafts Leonid Feldman, Jabir Mursi, Ilia Beberashvilli, Joshua Weissgarten. Nephrology Dept. Assaf Harofeh Medical Center, Zrifin Michal Shani. Sackler Faculty of Medicine, Tel Aviv Amir Peer, Arie Bass, Igor Rabin. Vascular Surgery Dept. Assaf Harofeh Medical Center, Zrifin 15:15 Evaluation of intact PTH in Heamodialyzed Patients with a third generation kit Sydney Benchetrit, Jacques Bernheim, Janice Green, Eliezer Golan Renal Physiology Laboratory, Dept. Of Nephrology and Hypertension Meir Medical Center, Kfar Saba 15:30 Occult HBV Infection in HD Patients? Ronit Geron, Galina Shkolnik, Olga Tanchilevsky, Irina Rubinchik Batya Kristal. Nephrology & Hypertansion Unit, Western Galilee Hospital, Nahariya Michal Carmiel-Haggai. Liver Unit, Western Galilee Hospital, Nahariya 15:45-16:15 Strategies to Increase the Use of Autogenous Arterio-venous Fistula in ESRD Dr. Arnold Miller, Assuta Medical Center 16:15-16:45 Break & Professional exhibition

3 16:45-18:30 Session 2: Clinical Nephrology (1) Chairpersons: Dr. Talia Weinstein, Dr. Noa Yanay 16:45 Urinary NGAL and KIM-1, Novel Biomarkers for Assessment of Acute Ischemic Kidney injury Following Nephron Sparing Surgery Zaid Abassi, Rima Sohotnik, Hoda Awad. Dept. Of Physiology, Faculty of Medicine, Technion, Haifa, Ofer Nativ. Dept. of Urology, Bnai Zion Hospital, Haifa 17:00 Consequences of treated versus untreated asymptomatic bacteriuria in the first year following kidney transplantation: a retrospective observational study Hefziba Green, Ruth Rahamimov, Elad Goldberg, Leonard Leibovici, Uzi Gafter, Eitan Mor. Rabin Medical Center, Petah-Tikva 17:15 Urinary NGAL (neutrophil gelatinase-associated lipocalin) for early detection of Acute Kidney Injury (AKI) in geriatric patients with urinary tract infection (UTI) treated by colistin Linda Shavit, Itzchak Slotki, Adult Nephrology Unit, Shaare Zedek Medical Center, Jerusalem Rackhel Manilov, Dept. of Geriatrics Shaare Zedek Medical Center, Jerusalem Yonit Wiener-Well, Infectious Diseases Unit Shaare Zedek Medical Center, Jerusalem Nurit Algur, Endocrinology laboratory Shaare Zedek Medical Center, Jerusalem 17:30 Renal excretion of uric acid and plasma levels of placental protein 13 at mid pregnancy may predict late preeclampsia Inbar Ben Shachar, Leonid Sirotinski. obst. gynec. Dept. Refael Gery. nephrology-hypertension unit Ziv medical center Safed Adi Nov. reaserch unit 17:45 Healthy subjects with low uric acid levels, followed up for 10 years, have a decreased incidence of diabetes and hypertension Adi Leiba, Dganit Dinour, Eli Holtzman. Nephrology and Hypertension Institute, Chaim Sheba Medical Center, Tel Hashomer Shlomo Vinker, Michal Shani. Dept. of Family Medicine, Clalit Health Services 18:00 Patterns and Frequency of Glomerular Diseases in Northern Israel-A Five Year Observational Study of Kidney Biopsies Marina Tchirkov, Tanya Mashiach, Ofer Ben Izhak, Suheir Assady. Rambam Medical Center, Haifa, Israel Roni Nasser. Rappaport Faculty of Medicine, Haifa 18:15 Nighttime heart rate is associated with high risk for cardiovascular disease. Alexander Kagan, Jayson Rapoport. Dept. of Nephrology and Hypertension, Kaplan Medical Center, Hebrew University, Jerusalem, and "Meuchedet" Sick Fund Hedy Faibel, Ishay Shoval. "Meuchedet" Sick Fund 18:30-19:15 Primary hyperoxaluria type III: A new kidney stone disease, the gene and the biochemical pathway Prof. Yacov Frishberg, Dept. of Pediatric Nephrology, Shaare Zedek Medical Center, Jerusalem

4 Day 2 Friday, April 20, :30-09:15 Session 3 Chairperson: Dr. Michal Elhalel Dranitzki 08:30-09:15 Advances in immunosuppression for renal transplantation Prof. Bernard Charpentier Faculty of Medicine Paris-South, University of Paris XI 09:15-10:15 Session 4 - Free Communication: Basic Science (1) chairpersons: Dr. Sydney Benchetrit Dr. Suheir Assady 09:15 Impaired renal growth hormone mediated JAK/STAT5 signaling in juvenile rats with chronic kidney disease Daniel Landau, Pediatrics, Soroka Medical Center and Ben Gurion University, Beer Sheva Debbie Weisel, Ariel Troib. Shraga Segal Dept. of Immunology, Ben Gurion University Leonid Katchko, Dept. of Pathology, Soroka Medical Center, Beer Sheva 09:30 Cyclosporine attenuates arginine transport, in human endothelial cells, through modulation of Cationic Amino Acid Transporter-1 Moshe Shashar, Ayelet Grupper*, Tamara Chernichovski, Yael Pri-Paz, Dganit Bakhri, Doron Schwartz, Talia Weinstein, Gil Chernin, Idit F. Schwartz. Nephrology Dept. Tel Aviv Sourasky Medical Center 09:45 The role of Uterine- Sensitization-Associated-Gene 1 (USAG1) in Renal Fibrosis Nomy Levin-Iaina, Vered Carmon, Eli J Holtzman. Dept. of nephrology and Hypertension, Sheba Medical Center, Tel Hashomer 10:00 Inhibition of dendritic cells-induced cytotoxic T-cells (CTLs) proliferation by adenosine Yair Cohen, Hadar Eini, Naamani Oshri, Cidio Chaimovitz, Dept. of Clinical Biochemistry, Ben-Gurion University of the Negev, Beer-Sheva Amos Douvdevani, Nephrology laboratory, Soroka Medical Center, Beer-Sheva 10:15-10:40 Break & Professional exhibition 10:40-12:10 Session 5 - The German-Israeli Session Chairpersons: Prof. Yoram Yagil, Dr. Gil Chernin Epigenetics of chronic progressive kidney disease Prof. Michael Zeisberg Göttingen University Medical Center, Göttingen, Germany The Molecular Pathogenesis of Nephronophthisis (NPH) Prof. Bernhard Schermer University of Cologne, Cologne, Germany

5 12:10-13:10 Session 6: Basic Science (2) Chairpersons: Prof. Amos Douvdevany, Prof. Daniel Landau 12:10 Gene Expression Analysis of the Therapeutic Effects of Vitamin D on Diabetic-like Conditions in Vascular smooth muscle cells Metsada Pasmanik-Chor, Varda Oron-Karni. Bioinformatics Unit, The G. S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv Janice Green, Sydney Benchetrit, Tali Zitman-Gal, Eliezer Golan, Jacques Bernheim Renal Physiology Laboratory, Dept. of Nephrology and Hypertension, Meir Medical Center, Kfar Saba 12:25 FXR or TGR5 Agonists Prevent High Glucose Mediated Glucolipotoxicity Renana Eshet-Leon, Michal Herman-Edelstein, Uzi Gafter. Rabin Medical center, Petah-tikva Pnina Scherzer. Hadassah Medical center, Jerusalem Moshe Levi, University of Colorado, Denver, CO, USA 12:40 The Molecular basis of a Novel Dent's-like disease a long-term enigma is finally resolved! Dganit Dinour, Liat Ganon, Pazit Bekerman, Zemach Eisenstein, and Eliezer J Holtzman Dept. of Nephrology and Hypertension, The Chaim Sheba Medical Center, Tel-Hashomer and the Sackler school of Medicine, Tel Aviv 12:55 Elevated urine heparanase levels are associated with proteinuria and decreased Renal allograft function. A Agbaria, I.F. Schwartz, M Boaz, R. Baruch, I. Shahaf, N. Ilan, I. Vlodavsky, T. Weinstein. Dep. Of Nephrology, Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Epidemiology Unit, E. Wolfsom Medical Center, Holon, Cancer and Vascular Biology Research Center, Bruce Rappaport Faculty fo Medicine, Technion, Haifa 13:10-14:05 Lunch &, Professional exhibition 14:05-15:35 Session 7: Clinical Nephrology (2) chairpersons Dr. Itzchak Slotki Dr. Zeev Kazir 14:05 Advanced Renal Magnetic Resonance Imaging (MRI) Methods During Impaired Kidney Function Rinat Abramovitz, Zohar Milman, Jonathan Axelrod, Nathalie Corchia. Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew Medical Center, Jerusalem Samuel Heyman. Dept. of Medicine, Hadassah Hebrew University Hospital, Mt. Scopus, Jerusalem 14:20 Oxidized Albumin, a Mediator and a Biomarker of Systemic Inflammation in Diabetic Nephropathy Regina Michelis, Shifra Sela, Galina Shapiro, Yoav Fridman. Eliachar Research Laboratory, Western Galilee Hospital, Nahariya Teuta Zeitun, Ronit Geron, Batya Kristal. Nephrology Dept. Western Galilee Hospital, Nahariya 14:35 Anti-Factor H Antibodies in A Patient with Membranoproliferative Glomerulonephritis Irit Krause, Amit Dagan, Miriam Davidivits. Institute of Pediatric Nephrology, Schneider Children Medical Center, Sackler Faculty of Medicine Tel-Aviv University Marie-Agnes Dragon-Durey, Veronique Fremeaux-Bacci. Service d'immunologic Biologique, Hopital Europeen Georges Pompidu, Assistance Publique-Hopitaux de Paris, Paris, France

14:50 Long term outcomes of Idiopathic Membranous Glomerulonephritis Treated with a unique protocol of Cyclosporine Kamal Hassan, Batya Kristal.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv Shadi Hassan. Internal Medicine Dep.

6 14:50 Long term outcomes of Idiopathic Membranous Glomerulonephritis Treated with a unique protocol of Cyclosporine Kamal Hassan, Batya Kristal. Nephrology and Hypertension Department-Western Galilee Hospital, Nahariya Balsam Kot. The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa Fadi Hassan. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv Shadi Hassan. Internal Medicine Dep. Carmel Medical Center, Haifa 15:05 Prevalence of Vitamin D Deficiency among Kidney recipients in Israel Evaluation of Associated Factors Ophir Eyal, Michal Aharon, Michal Dranitzki Elhalel. Nephrology and Hypertension Services, Hadassah - Hebrew University Medical Center, Jerusalem 15:20-15:35 Break & Professional exhibition 15:40-16:30 Debate: Salt restriction in the general population and hypertensive patients. For: prof. Jayson Rapoport, Dept. of Nephrology and Hypertension, Kaplan Medical Center, Rehovot Agianst: Dr. Gil Chernin, Dept. of Nephrology, Tel Aviv Sourasky Medical Center 16:30-17:30 Session 8 - ISNH General Assembly Day 3 Saturday, April 21, :00-12:30 Session 9 Chairpersons: Dr. Talia Weinstein, Dr. Eliezer Golan 10:00 The future of Nephrology in Isreal Is there any? 11:15 Nephrolgy and Earthquake are we ready? הכנס

Dr. Eliezer Golan, President, ISNH. Meir Medical Center, Kfar Saba Dr. Talia Weinstein, Vice-President, ISNH. Sourasky Medical Center, Tel Aviv

Organizing Committee Dr. Eliezer Golan, President, ISNH. Meir Medical Center, Kfar Saba Dr. Talia Weinstein, Vice-President, ISNH. Sourasky Medical Center, Tel Aviv Scientific Committee Dr. Suheir Assady,